About the job
Technology Innovation Institute (TII) is a publicly funded research institute, based in Abu Dhabi, United Arab Emirates. It is home to a diverse community of leading scientists, engineers, mathematicians, and researchers from across the globe, transforming problems and roadblocks into pioneering research and technology prototypes that help move society ahead.
Biotechnology Research Centre
The Biotechnology Research Center (BRC), part of the Technology Innovation Institute (TII), was established to contribute to UAE research priorities across several emerging fields, utilizing molecular, cellular and digital technologies to develop the human expertise and biotech sovereignty of the emirates. The BRC is addressing unmet needs in advanced bio-robotics, in environmental applications such as new desalination and agricultural technologies, and it aims to enable better healthcare outcomes through molecular and genomic strategies, and AI enhanced bioinformatics and biomedicine.
Job Responsibilities:
Develop PK/PD or PB/PK or QSP mathematical models to describe the ADME effects of drugs.
Use available methods for parameter estimation, sensitivity analysis, assessment of model credibility.
Collaborate with the biotech center (BRC) wet-lab facilities to request/conduct bio-chemical experiments necessary to set up and to validate the pharmacometrics models.
Be involved in scouting activities in local/international pharmaceutical companies to identify exploitable results.
Contribute to securing relevant Intellectual Property on the team’s projects
Assist team members with constructive criticisms of manuscripts preparation, rehearsals of talks, etc.
Contribute to team meetings by reporting ongoing works and giving feedback to colleagues on their progress reports.
Maintain a technology watch on emerging biotech trends in his/her area of expertise and disseminate the relevant information to team members.
Contribute to outreach activities directed to the public, during science fairs, students’ visits, and for relevant public events.
Generally, contribute to fostering a friendly and productive group relationship.
Requirements:
Minimum of 2 years of research/industry experience in the development of PK/PD, PB/PK or QSP models
Good level knowledge of specific pharmacometrics and systems pharmacology software tools (e.g., NONMEM, PKSIM, MonolixSuite)
Basic understanding of molecular and cell biology
Good level knowledge of computer programming in a high-level environment (e.g., R, Matlab, Python) is a plus
Good-level knowledge clinical trial pharmacometrics
Good track record of scientific publications
Prior work with regulatory filings in a pharmaceutical company is a plus
Demonstrable abilities for effective English written and oral communication.
Qualifications:
PhD in fundamental pharmacokinetics, pharmacokinetic-pharmacodynamic modeling, and pharmacometrics principles.
Master’s Degree in a relevant field preferred.
At TII, we help society to overcome its biggest hurdles through a rigorous approach to scientific discovery and inquiry, using state-of-the-art facilities and collaboration with leading international institutions. Our rigorous discovery and inquiry-based approach helps to forge new and disruptive breakthroughs in advanced materials, autonomous robotics, cryptography, digital security, directed energy, quantum computing and secure systems.
Please contact Andrea Tortosa (andrea.tortosa@tii.are) for candidature or further info.
